Born into a family of musicians, Yefren began his musical studies at the age of 12 in the trumpet class of Professor Pacho Flores, and in the socio-educational program EL SISTEMA in San Cristóbal (state of Táchira), Venezuela.

He continued his instrumental studies with professors Gentil Ramírez and Jairo Hernández. He entered the Orquesta Infantil and Juvenil Luis Gilberto Mendoza and at the age of 16, the Orquesta Sinfónica Simón Bolívar de Táchira. One year later, he started at the Orquesta Sinfónica Teresa Carreño in Venezuela.

Also playing trombone and euphonium as part of his academic training, he decided to specialize in euphonium, a relatively new appearing instrument that offers a wide range of creative possibilities and technical and musical development.

Over the course of his career, he has been part of prestigious orchestras such as the Simón Bolívar Wind Band Orchestra, the Venezuelan Brass Ensemble, the Paris Brass Band as a guest. He has toured in Latin America, in the United States, in Europe and on the Asian continent.

He graduated from the class of Bastien Baumet at the CRR of Paris in 2018 with the maximum honors from the jury. Then, he won the gold medal at the European Grand Duke Adolphe Young Soloists Competition in 2016.

He currently directs his own brass classes in various conservatories and music schools in Paris.